Congenital Heart Disease USMLE Step 1 Practice Question
A 3-month-old infant with hypotonia, upslanting palpebral fissures, and a single transverse palmar crease presents with poor feeding and tachypnea. Vital signs show HR 155/min, RR 48/min, BP 65/42 mmHg, and SpO2 92% on room air. Chest X-ray demonstrates cardiomegaly with pulmonary edema. Echocardiography reveals a common atrioventricular valve with primum and secundum atrial septal defects plus a ventricular septal defect. No cyanosis is currently present. Which diagnosis best explains these findings?
Answer choices
- ACoarctation of the aorta
- BTransposition of the great arteries
- CPatent ductus arteriosus
- DEndocardial cushion defectCorrect answer
- ETetralogy of Fallot
- FIsolated ventricular septal defect without AV valve involvement
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