Congenital Heart Disease USMLE Step 1 Practice Question
A 2-day-old premature newborn (34 weeks gestation) presents with tachypnea (RR 68/min), poor weight gain, and feeding intolerance. Vital signs show BP 58/32 mmHg, HR 162/min, and SpO2 98% on room air. Cardiac examination reveals a continuous "machine-like" murmur at the left infraclavicular region. Chest X-ray demonstrates pulmonary edema and cardiomegaly. No cyanosis is noted. Which medication would most likely promote closure of the patent ductus arteriosus?
Answer choices
- AIndomethacinCorrect answer
- BProstaglandin E1 infusion
- CFurosemide
- DDobutamine
- EMilrinone
- FSildenafil
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