Cardiovascular Drugs USMLE Step 1 Practice Question
A 55-year-old man with hypertension has been on hydrochlorothiazide monotherapy for 2 years. He presents with blood pressure 148/92 mmHg, heart rate 78/min, and denies dyspnea. Laboratory studies reveal serum potassium 3.2 mEq/L (normal 3.5–5.0), serum glucose 145 mg/dL, and serum uric acid 7.8 mg/dL. Urinalysis shows no proteinuria. Which drug would most appropriately address his hypokalemia, hyperglycemia, and hyperuricemia?
Answer choices
- AChlorthalidone
- BHydralazine
- CMetoprolol
- DAmlodipine
- ESpironolactoneCorrect answer
- FEplerenone
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