Cardiovascular Drugs USMLE Step 1 Practice Question
A 70-year-old man with acute decompensated heart failure presents with dyspnea, orthopnea, and bilateral ankle edema. Vital signs show BP 165/95 mmHg, HR 102 bpm, RR 22/min, temp 37.2°C, SpO2 92% on room air. Chest X-ray reveals pulmonary edema. BNP is elevated at 850 pg/mL. He receives intravenous furosemide and rapidly produces 2 liters of urine within 2 hours. Troponin is normal. Which transporter system is directly inhibited by this medication?
Answer choices
- ANa K 2Cl cotransporter in the thick ascending limbCorrect answer
- BNa Cl cotransporter in the distal convoluted tubule
- CSodium glucose cotransporter in the proximal tubule
- DEpithelial sodium channel in the collecting duct
- ECarbonic anhydrase in the proximal tubule
- FAquaporin-2 water channel in the collecting duct
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