Autonomic Pharmacology USMLE Step 1 Practice Question
A 19-year-old college student presents with severe occipital headache, profuse diaphoresis, and substernal chest pain after consuming tyramine-rich aged cheese while taking an antidepressant. Vital signs show BP 210/140 mmHg, HR 118 bpm, RR 22/min, temperature 37.8°C, and SpO2 98% on room air. Serum troponin is normal. He denies recent medication changes besides antidepressant initiation two weeks ago. Which antidepressant class most likely caused this hypertensive crisis?
Answer choices
- ASelective serotonin reuptake inhibitor
- BTricyclic antidepressant
- CSerotonin-norepinephrine reuptake inhibitor
- DMonoamine oxidase inhibitorCorrect answer
- EAtypical antipsychotic
- FNorepinephrine-dopamine reuptake inhibitor
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