Autonomic Pharmacology USMLE Step 1 Practice Question
A 52-year-old man with resistant hypertension uncontrolled on lisinopril and hydrochlorothiazide is started on a centrally acting sympatholytic agent at 0.1 mg twice daily. Two weeks later, he presents with dry mouth, daytime somnolence, and mild bradycardia (HR 58/min). Current vital signs show BP 128/76 mmHg, temperature 37.1°C, and RR 14/min. Physical examination reveals mildly reduced salivation and no peripheral edema. Laboratory studies reveal normal electrolytes and renal function. He denies orthostatic symptoms. Which medication was most likely prescribed?
Answer choices
- APhenoxybenzamine
- BMetoprolol
- CClonidineCorrect answer
- DHydralazine
- EPrazosin
- FGuanfacine
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