Autonomic Pharmacology USMLE Step 1 Practice Question
A 69-year-old man with COPD presents with exertional dyspnea and chronic productive cough for the past 8 months. Vital signs show BP 148/92 mmHg, HR 88/min, RR 22/min, SpO2 88% on room air. Spirometry reveals an FEV1/FVC ratio of 0.58. On exam, he has diminished breath sounds bilaterally and a prolonged expiratory phase. He receives inhaled tiotropium, an anticholinergic medication that blocks vagally mediated bronchoconstriction. Chest X-ray shows hyperinflation without acute infiltrates. He denies urinary symptoms. Which of the following adverse effects is most likely with this therapy?
Answer choices
- ADry mouthCorrect answer
- BOtotoxicity
- CHyperkalemia
- DTendon rupture
- EPulmonary fibrosis
- FUrinary retention
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