Asthma USMLE Step 1 Practice Question
A 61-year-old man with a history of Hodgkin lymphoma underwent mediastinal radiation therapy 7 months ago. He now presents with progressive dyspnea and dry cough. Vital signs show BP 138/82 mmHg, HR 102 bpm, RR 22/min, SpO2 92% on room air, and temperature 37.2°C. CT chest demonstrates fibrotic changes confined to the irradiated field. Pulmonary function tests show reduced DLCO. He denies fever or productive sputum. Which diagnosis best explains these findings?
Answer choices
- ARadiation induced pulmonary fibrosisCorrect answer
- BChylothorax
- CUsual interstitial pneumonia unrelated to therapy
- DDiffuse alveolar hemorrhage
- EAcute eosinophilic pneumonia
- FRadiation-induced pericarditis with constrictive physiology
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