Antimicrobials USMLE Step 1 Practice Questions
55 board-style USMLE Step 1 questions in Pharmacology. Each question shows the correct answer; create a free account for the full explanation and adaptive practice.
- USMLE Step 1 Ā· medium25. A 5-year-old boy with acute bacterial meningitis due to Streptococcus pneumoniae is treated with ceftriaxone and vancomycin. On hospital day 2, he develops a diffuse maculopapulā¦
- USMLE Step 1 Ā· medium26. A 42-year-old man with newly diagnosed HIV infection presents to clinic for initiation of antiretroviral therapy. CD4+ count is 150 cells/Ī¼L, and viral load is 180,000 copies/mLā¦
- USMLE Step 1 Ā· medium27. A 55-year-old man with newly diagnosed pulmonary tuberculosis (chest X-ray showing left upper lobe infiltrate) is started on isoniazid, rifampin, pyrazinamide, and ethambutol. Tā¦
- USMLE Step 1 Ā· medium28. A 45-year-old woman with a history of rash following amoxicillin 10 years ago presents to the emergency department with a 3-day history of productive cough with purulent sputum,ā¦
- USMLE Step 1 Ā· medium29. A 68-year-old man with stage 4 chronic kidney disease (baseline creatinine clearance 22 mL/min) presents with dysuria, urinary frequency, and suprapubic pain. Urinalysis shows pā¦
- USMLE Step 1 Ā· medium30. A 32-year-old woman with community-acquired pneumonia presenting with fever (38.9Ā°C), cough, and dyspnea is prescribed azithromycin. On day 4 of therapy, she develops severe craā¦
- USMLE Step 1 Ā· hard31. A 34-year-old woman with HIV infection (CD4 count 45 cells/Ī¼L) on antiretroviral therapy presents with a 3-day history of fever (39.2Ā°C), severe headache, and neck stiffness. Ceā¦
- USMLE Step 1 Ā· medium32. A 64-year-old man with chronic kidney disease (baseline creatinine 2.1 mg/dL, CrCl 25 mL/min) presents to the hospital with fever (38.9Ā°C), hypotension (88/54 mmHg), and tachycaā¦
- USMLE Step 1 Ā· medium33. A 3-year-old child with acute otitis media presents with fever (39.2Ā°C), HR 120/min, and otalgia. Cultures identify penicillin-resistant Streptococcus pneumoniae. He is prescribā¦
- USMLE Step 1 Ā· hard34. A 58-year-old woman is brought to the emergency department with fever, rigors, and altered mental status for the past 12 hours. Her temperature is 39.4Ā°C, blood pressure is 88/6ā¦
- USMLE Step 1 Ā· medium35. A 34-year-old man with HIV/AIDS and a CD4 count of 45 cells/Ī¼L presents to the emergency department with a 5-day history of progressive dyspnea, nonproductive cough, and fever tā¦
- USMLE Step 1 Ā· hard36. A 71-year-old man with chronic kidney disease (eGFR 25 mL/min/1.73mĀ²) presents with severe bilateral Achilles tendon pain on day 3 of levofloxacin 500 mg daily for urinary tractā¦
- USMLE Step 1 Ā· medium37. A 62-year-old woman with a history of type 2 diabetes mellitus and a methicillin-resistant Staphylococcus aureus skin and soft tissue infection of the right lower extremity is pā¦
- USMLE Step 1 Ā· hard38. A 19-year-old man with bacterial meningitis presents with fever (39.2Ā°C), headache, and neck stiffness. Vital signs show BP 118/76, HR 104, RR 18, SpO2 98% on room air. He receiā¦
- USMLE Step 1 Ā· medium39. A 24-year-old man presents with urethritis and dysuria; urine culture confirms Neisseria gonorrhoeae. He is prescribed ciprofloxacin 500 mg orally twice daily. Vital signs are sā¦
- USMLE Step 1 Ā· hard40. A 42-year-old woman with HIV infection (CD4 200 cells/Ī¼L) presents with fever, headache, and positive blood culture for Cryptococcus neoformans. Vital signs: BP 118/76, HR 102,ā¦
- USMLE Step 1 Ā· easy41. A 67-year-old man with COPD presents with community-acquired pneumonia. Vital signs show HR 102, RR 22, SpO2 88% on 2L oxygen, BP 128/76, and temperature 38.5Ā°C. Sputum cultureā¦
- USMLE Step 1 Ā· hard42. A 41-year-old man with severe acne is prescribed isotretinoin and concurrently takes doxycycline for secondary bacterial infection. He develops severe frontal headache, blurredā¦
- USMLE Step 1 Ā· easy43. A 19-year-old previously healthy woman presents with sudden onset fever (39.8Ā°C), severe headache, and petechial rash. Vital signs show BP 98/62, HR 118, RR 22, SpO2 98% on roomā¦
- USMLE Step 1 Ā· hard44. A 30-year-old pregnant woman with HIV infection started on zidovudine (AZT) for vertical transmission prophylaxis presents with progressive fatigue and dyspnea on exertion. Vitaā¦
- USMLE Step 1 Ā· medium45. A 25-year-old man presents to his primary care physician with a 3-day history of painful grouped vesicles on the shaft of the penis associated with mild fever, malaise, and tendā¦
- USMLE Step 1 Ā· hard46. A 36-year-old man with acute myelogenous leukemia undergoing induction chemotherapy develops persistent fever to 39.4Ā°C despite seven days of broad-spectrum antibiotics, includiā¦
- USMLE Step 1 Ā· hard47. A 39-year-old woman with newly diagnosed tuberculosis begins standard four-drug therapy including rifampin. Within days, she notices orange discoloration of her urine and contacā¦
- USMLE Step 1 Ā· medium48. A 42-year-old man with active pulmonary tuberculosis is on antimicrobial therapy. After 6 weeks of treatment, he develops progressive numbness and tingling in his feet bilateralā¦