Acute Kidney Injury USMLE Step 1 Practice Question
A 63 year old man with long standing rheumatoid arthritis develops generalized edema and frothy urine. Urinalysis shows heavy proteinuria. Serum creatinine is mildly elevated. Renal biopsy demonstrates amorphous eosinophilic extracellular deposits that show apple green birefringence under polarized light after Congo red staining. Which of the following is the most likely diagnosis?
Answer choices
- AMembranoproliferative glomerulonephritis
- BFocal segmental glomerulosclerosis
- CAA amyloidosis involving the kidneyCorrect answer
- DAcute interstitial nephritis
- EMinimal change disease
- FAL amyloidosis from plasma cell dyscrasia with lambda light chain deposits
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